The need for systematic quality controls in implementing N95 reprocessing and sterilizationArticle Published on 2023-03-012023-07-11 Journal: The Journal of hospital infection [Category] COVID19(2023년), [키워드] COVID-19 Hospital safety infection control Mask reprocessing N95 pandemic Quality control Quality improvement SARS-CoV-2 Sterilization. [DOI] 10.1016/j.jhin.2022.11.023 PMC 바로가기
Highly sensitive and rapid detection of SARS-CoV-2 via a portable CRISPR-Cas13a-based lateral flow assayArticle Published on 2022-12-012022-11-15 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome addition amplification approach assays clinical sample comparable component Concentration coronavirus disease Coronavirus-2 COVID-19 CRISPR Diagnostic method Effectiveness ENhance examined identify immunochromatographic IMPROVE individual isothermal lateral flow lateral flow assay lateral flow strip limit of detection molecular polymerase chain primer probe Protein provide Quality control reliability Result reverse transcription RNA RT-PCR SARS-CoV-2 screened sensitive detection. sensitivity significantly Spread tested virus detection [DOI] 10.1002/jmv.28096 PMC 바로가기
Analysis of the mutation dynamics of SARS-CoV-2 genome in the samples from Georgia State of the United States미국 조지아주 샘플에서 SARS-CoV-2 게놈의 돌연변이 역학 분석Article Published on 2022-10-202022-09-11 Journal: Gene [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Algorithm Amino acid analysis Analysis caused China clade clades Complete coronavirus disease Coronavirus disease 2019 Coronavirus-2 country Course COVID-19 D614G determine disease England Europe Filter Genome genome sequence Genome sequences Host indicate limit majority Multiple Multiple studies mutated Mutation N501Y NCBI database Novel coronavirus novel coronavirus SARS-CoV-2 nucleotide nucleotides online tool over P681H pandemic Phylogenetic Quality control reference genome SARS-CoV-2 SARS-CoV-2 genome SARS-CoV2 sequence Sequence alignment sequenced genomes sequences severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 severe acute respiratory syndrome coronavirus-2. Spread state survival the United State the WHO translation Transmission variant variants virus was used Wuhan [DOI] 10.1016/j.gene.2022.146774 PMC 바로가기 [Article Type] Article
Two Years of Genomic Surveillance in Belgium during the SARS-CoV-2 Pandemic to Attain Country-Wide Coverage and Monitor the Introduction and Spread of Emerging VariantsArticle Published on 2022-10-202022-11-15 Journal: Viruses [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, 진단, [키워드] Belgium country COVID-19 effort genomic genomic sequencing Genomic surveillance intensity Laboratory Lineage Next-generation sequencing performed Quality control Research SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomic surveillance Surveillance the SARS-CoV-2 variant variants of concern variants of concern. Year [DOI] 10.3390/v14102301 PMC 바로가기
Prevention of ribosome collision-induced neuromuscular degeneration by SARS CoV-2-encoded Nsp1Article Published on 2022-10-182022-11-16 Journal: Proceedings of the National Academy of Sciences of [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] ABCE1 abort acute respiratory syndrome affecting AKT Alzheimer’s disease autophagy biochemical analysis combating condition coronavirus COVID-19 pandemic Critical disease Diseases Drosophila effective exhibited Factors Genetic Host hosts mechanism modify neurodegenerative nonstructural protein 1 nsp1 overexpression pathogenic mechanism phenotype prevention Protein Quality control quality-control rescued Research ribosome collision ribosome-associated quality control. ribosomes SARS-CoV-2 Signaling specificity therapeutic strategy translation Treatment virus [DOI] 10.1073/pnas.2202322119 PMC 바로가기
Considerations for the selection of tests for SARS-CoV-2 molecular diagnosticsArticle Published on 2022-10-012022-11-15 Journal: Molecular biology reports [Category] COVID19(2023년), SARS, 유전자 메커니즘, 진단, 치료기술, 치료제, [키워드] Accuracy authorization chain clinical country Course COVID-19 criteria detect develop diagnostic Diagnostic performance diagnostic test diagnostics drug evaluated food gold standard good manufacturing practice Guidance independent Infection information Laboratory lack molecular molecular test Mutation Novel coronavirus outbreak pandemic proportion Quality control reaction real-time RT-PCR Region regions regulatory authority required respiratory SARS-CoV-2 SARS-CoV-2 test selected Spread target gene Test Test selection. variable [DOI] 10.1007/s11033-022-07455-5 PMC 바로가기
Ethnicity, Comorbid Medical Conditions, and SARS-CoV-2 Test Cycle Thresholds in the Veteran PopulationArticle Published on 2022-10-012022-11-15 Journal: Journal of racial and ethnic health disparities [Category] COVID19(2023년), SARS, 진단, [키워드] access Access to health care addition Admission affected African American age Care center clinical Clinical course Clinical pathology collected COVID-19 COVID-19 infection cycle difference disease severity Ethnic groups Ethnicity Factors Gender Health ICU care increases in information Intensive Medical conditions Molecular pathology outcome Patient Philadelphia polymerase chain Population Population demographics positive public health Quality Quality assurance Quality control required Research retrospective RT-PCR SARS-CoV-2 SARS-CoV-2 RT-PCR test SARS-CoV-2. significantly statistically significant Test tested transcriptase veteran Viral load viral loads was performed [DOI] 10.1007/s40615-021-01114-4 PMC 바로가기
Leukocytapheresis variables and transit time for allogeneic cryopreserved hpc: better safe than sorryArticle Published on 2022-10-012022-11-15 Journal: Bone marrow transplantation [Category] 바이오마커, [키워드] Allogeneic Analysis attribute CD3 CD34 Cell cells CFU-GM Characteristics Clinical outcome Collection Contamination correlated correlation COVID-19 pandemic cryopreservation group hematopoietic progenitor cell indicated investigated nucleated cell pandemic Patient Peripheral blood prevented Quality control raised Red cell remained Safe shown statistically significant thawing Univariate analysis variable Volume [DOI] 10.1038/s41409-022-01750-2 PMC 바로가기
Development and Analytical Validation of a One-Step Five-Plex RT-ddPCR Assay for the Quantification of SARS-CoV-2 Transcripts in Clinical SamplesArticle Published on 2022-09-132022-11-16 Journal: Analytical Chemistry [Category] SARS, 치료기술, [키워드] analytical sensitivity Analytical specificity analyzed applied calibrator Characteristics clinical Concordance controls correlation COVID-19 pandemic development Direct DNA and RNA in-silico Inclusion Internal control linear methodology Metrics molecular primer probe provide Quality control quantification Region reproducibility RNA RT-qPCR Sample SARS-CoV-2 SARS-CoV-2 detection sensitivity Spearman specimen Standardization transcripts validation viral concentrations [DOI] 10.1021/acs.analchem.2c00868 PMC 바로가기
Deciphering SARS CoV-2-associated pathways from RNA sequencing data of COVID-19-infected A549 cells and potential therapeutics using in silico methodsArticle Published on 2022-09-022022-11-16 Journal: Medicine [Category] SARS, 유전자 메커니즘, [키워드] A549 cell activated Activation acute respiratory syndrome addition Analysis Atypical candidate caused characterized CLC complications CoV COVID COVID-19 COVID-19 infection cytokine deaths DEGs Determining differentially expressed gene disease drug effective experimental validation Gene Expression Omnibus gene signatures Genomics GEO GSE147507 human-to-human transmission identify IFNβ IL-17 IL-1β Illumina in silico In silico method influenza A Interaction interferon beta interferon regulatory factor IRF3 IRF9 JQ1 knowledge mechanism Methylprednisolone mock-treated pathology pathway Pneumonia Prednisolone Quality control receptors RNA RNA sequencing RNA sequencing data SARS CoV-2 signaling pathway signaling pathways small molecule STAT2 the Coronaviridae the disease therapy Transcription Treatment underlying disease upstream Viral protein virus infection was used with COVID-19 Wuhan, China [DOI] 10.1097/MD.0000000000029554 PMC 바로가기